Would you rather be intrusive or irrelevant?

This may sound counterintuitive:

Maybe [advertising is] about having something interesting to say and somewhere intrusive to say it.

But is it? The Ad Contrarian, where I found this quote, thinks not. And the truth is, working with social media and defending the ever-so-perfect permission marketing, it ressonated with me. I'm all about permission, but who cares about permission if you have nothing interesting to say? And here's some food for thought: if you could only choose relevant/intrusive vs irrelevant/permition, which would you choose?